1407-1416
| Discovery and Synthesis of [6-Hydroxy-3-[4-[2-(1-piperidinyl)ethoxy]phenoxy]- 2-(4-hydroxyphenyl)]benzo[b]thiophene: A Novel, Highly Potent, Selective Estrogen Receptor Modulator
Alan D. Palkowitz,
Andrew L. Glasebrook,
K. Jeff Thrasher,
Kenneth L. Hauser,
Lorri L. Short,
D. Lynn Phillips,
Brian S. Muehl,
Masahiko Sato,
Pamela K. Shetler,
George J. Cullinan,
Tina R. Pell, and
Henry U. Bryant
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1417-1421
| Novel Heterocyclic-Fused Pyridazinones as Potent and Selective Phosphodiesterase IV Inhibitors
Vittorio Dal Piaz,
Maria Paola Giovannoni, and
Carla Castellana
, José Maria Palacios,
Jorge Beleta,
Teresa Doménech, and
Victor Segarra
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1422-1438
| Conformationally Constrained [p-( -Aminoalkyl)phenacetyl]-L-seryl-L-lysyl Dipeptide Amides as Potent Peptidomimetic Inhibitors of Candida albicans and Human Myristoyl-CoA:Protein N-Myristoyl Transferase
Srinivasan R. Nagarajan,
Balekudru Devadas,
Mark E. Zupec,
Sandra K. Freeman,
David L. Brown,
Hwang-Fun Lu,
Pramod P. Mehta,
Nandini S. Kishore,
Charles A. McWherter,
Daniel P. Getman,
Jeffrey I. Gordon, and
James A. Sikorski
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1439-1446
| Synthesis and Structure-Activity Relationships of 17 -Substituted 14-Hydroxysteroid 3-( -L-Rhamnopyranoside)s: Steroids That Bind to the Digitalis Receptor
John F. Templeton,
Yangzhi Ling,
Kirk Marat, and
Frank S. LaBella
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1447-1454
| Dihydro(alkylthio)(naphthylmethyl)oxopyrimidines: Novel Non-Nucleoside Reverse Transcriptase Inhibitors of the S-DABO Series
Antonello Mai,
Marino Artico,
Gianluca Sbardella,
Silvana Quartarone,
Silvio Massa,
Anna G. Loi,
Antonella De Montis,
Franca Scintu,
Monica Putzolu, and
Paolo La Colla
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1455-1464
| Smart Region Definition: A New Way To Improve the Predictive Ability and Interpretability of Three-Dimensional Quantitative Structure-Activity Relationships
Manuel Pastor,
Gabriele Cruciani, and
Sergio Clementi
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1465-1474
| Improved P1/P1' Substituents for Cyclic Urea Based HIV-1 Protease Inhibitors: Synthesis, Structure-Activity Relationship, and X-ray Crystal Structure Analysis
David A. Nugiel,
Kim Jacobs,
Lyndon Cornelius,
Chong-Hwan Chang,
Prabhakar K. Jadhav,
Edward R. Holler,
Ronald M. Klabe,
Lee T. Bacheler,
Beverly Cordova,
Sena Garber,
Carol Reid,
Kelly A. Logue,
Lorraine J. Gorey-Feret,
Gilbert N. Lam,
Susan Erickson-Viitanen,
Steven P. Seitz
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1475-1494
| A Comparison of Structure-Activity Relationships between Spermidine and Spermine Analogue Antineoplastics
Raymond J. Bergeron,
Yang Feng,
William R. Weimar,
James S. McManis,
Hristina Dimova,
Carl Porter,
Brian Raisler, and
Otto Phanstiel
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1495-1510
| Folate-Based Inhibitors of Thymidylate Synthase: Synthesis and Antitumor Activity of  -Linked Sterically Hindered Dipeptide Analogues of 2-Desamino-2-methyl-N10-propargyl-5,8-dideazafolic Acid (ICI 198583)
Vassilios Bavetsias,
Ann L. Jackman,
Jonathan H. Marriott,
Rosemary Kimbell,
William Gibson,
F. Thomas Boyle, and
Graham M. F. Bisset
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1511-1518
| Synthesis, Antiviral Activity, and Biological Properties of Vinylacetylene Analogs of Enviroxime
Frantz Victor,
Thomas J. Brown,
Kristina Campanale,
Beverly A. Heinz,
Lisa A. Shipley,
Kenneth S. Su,
Joseph Tang,
Lori M. Vance, and
Wayne A. Spitzer
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1519-1529
| Tyrosine Kinase Inhibitors. 11. Soluble Analogues of Pyrrolo- and Pyrazoloquinazolines as Epidermal Growth Factor Receptor Inhibitors: Synthesis, Biological Evaluation, and Modeling of the Mode of Binding
Brian D. Palmer,
Susanne Trumpp-Kallmeyer,
David W. Fry,
James M. Nelson,
H. D. Hollis Showalter, and
William A. Denny
[Full Article -
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1530-1538
| Inhibition of Thyroid Hormone Uptake by Calcium Antagonists of the Dihydropyridine Class
Gerhard H. Scholz,
Silke Vieweg,
Mathias Uhlig,
Michael Thormann,
Peter Klossek,
Siegfried Goldmann, and
Hans-Jörg Hofmann
[Full Article -
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1539-1549
| Binding Affinities for Sulfonamide Inhibitors with Human Thrombin Using Monte Carlo Simulations with a Linear Response Method
Deborah K. Jones-Hertzog and
William L. Jorgensen
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1550-1558
| Preparation and Anti-HIV Activity of N-3-Substituted Thymidine Nucleoside Analogs
David R. Adams,
Caroline Perez,
Michel Maillard,
Jean-Claude Florent,
Michel Evers,
Yvette Hénin,
Simon Litvak,
Laura Litvak,
Claude Monneret, and
David S. Grierson
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1559-1559
| Selection, Preparation and Pharmacological Evaluation of Plant Material By Elizabeth M. Williamson, David T. Okpako, and Fred J. Evans. John Wiley & Sons, Chichester, U.K. 1996. ix + 228 pp. 15.5 × 23.5 cm. ISBN 0-471-94217-0. $39.95 (pbk).
Maurice Shamma
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1559-1560
| Chemistry and Toxicology of Diverse Classes of Alkaloids Edited by Murray S. Blum. Alaken, Inc., Fort Collins, Co. 1996. 386 pp. 16 × 23.5 cm. ISBN 1-880293-04-8. $99.50.
Maurice Shamma
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1560-1560
| Enantiomers of Diastereoisomeric cis-N-[1-(2-Hydroxy-2-phenylethyl)-3-methyl-4-piperidyl]-N-phenylpropanamides: Synthesis, X-ray Analysis, and Biological Activities
George A. Brine,
Peter A. Stark,
Young Liu,
F. Ivy Carroll,
P. Singh,
Heng Xu,
Richard B. Rothman
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1560-1560
| Conformationally Constrained Analogues of Diacylglycerol. 13. Protein Kinase C Ligands Based on Templates Derived from 2,3-Dideoxy-L-erythro(threo)-hexono-1,4-lactone and 2-Deoxyapiolactone
Jeewoo Lee,
Nancy E. Lewin,
Peter Acs,
Peter M.
Blumberg, and
Victor E. Marquez
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